Comparing methods using a prediction interval

Differences between confidence intervals and prediction intervals explained
In this post, I will illustrate the use of prediction intervals for the comparison of measurement methods. In the example a new spectral method for measuring whole blood hemoglobin is compared with a reference method. First, let’s start with discussing the large difference between a confidence interval and a prediction interval. Prediction interval versus Confidence […]

Taking the baseline measurement into account

constrained LDA in R
In Randomized Controlled Trials (RCTs), a “Pre” measurement is often taken at baseline (before randomization), and treatment effects are measured at one or more time point(s) after randomization (“Post” measurements). There are many ways to take the baseline measurement into account when comparing 2 groups in a classic pre-post design with one post measurement. In […]